Category: Medications - Page 4

Lot-to-Lot Variability in Biologics and Biosimilars: Why Differences Between Batches Are Normal and Safe

Posted By John Morris    On 10 Dec 2025    Comments (12)

Lot-to-Lot Variability in Biologics and Biosimilars: Why Differences Between Batches Are Normal and Safe

Lot-to-lot variability is a natural part of biologics and biosimilars due to their complex production in living cells. Unlike generics, biosimilars aren't identical copies - but they're proven safe and effective despite natural batch differences.

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Replicate Study Designs: Advanced Methods for Bioequivalence Assessment

Posted By John Morris    On 2 Dec 2025    Comments (9)

Replicate Study Designs: Advanced Methods for Bioequivalence Assessment

Replicate study designs are essential for accurately assessing bioequivalence of highly variable drugs. Learn how TRT/RTR and TRRT/RTRT designs reduce sample sizes, meet regulatory standards, and improve generic drug safety.

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Medical Society Guidelines on Generic Drug Use: What Doctors Really Think

Posted By John Morris    On 1 Dec 2025    Comments (9)

Medical Society Guidelines on Generic Drug Use: What Doctors Really Think

Medical societies have conflicting stances on generic drug substitution. While most generics are safe, neurologists and other specialists warn against switching certain high-risk medications due to potential safety risks. Here's what doctors really think.

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How to Request a Lower-Cost Therapeutic Alternative Medication

Posted By John Morris    On 28 Nov 2025    Comments (8)

How to Request a Lower-Cost Therapeutic Alternative Medication

Learn how to ask your doctor for a lower-cost therapeutic alternative medication that works just as well but saves you hundreds a month. Real strategies, real savings, no fluff.

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Patient Counseling on Generics: What Pharmacists Must Discuss to Improve Adherence and Trust

Posted By John Morris    On 22 Nov 2025    Comments (18)

Patient Counseling on Generics: What Pharmacists Must Discuss to Improve Adherence and Trust

Pharmacists must clearly explain generic medications to patients to prevent non-adherence, reduce fears, and ensure safety. Learn the legal requirements, key talking points, and proven strategies to build trust and improve outcomes.

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Rheumatoid Arthritis Medications: Understanding DMARD and Biologic Interactions

Posted By John Morris    On 21 Nov 2025    Comments (12)

Rheumatoid Arthritis Medications: Understanding DMARD and Biologic Interactions

Understanding how DMARDs and biologics interact in rheumatoid arthritis treatment is key to controlling the disease. Learn about methotrexate combinations, biosimilars, JAK inhibitors, and real-world choices patients make.

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Liquid Antibiotics and Reconstituted Suspensions: Why They Expire So Fast

Posted By John Morris    On 20 Nov 2025    Comments (15)

Liquid Antibiotics and Reconstituted Suspensions: Why They Expire So Fast

Liquid antibiotics expire quickly after mixing - usually within 10 to 14 days. Learn why they break down so fast, how to store them safely, and what happens if you use them past their date.

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Hydroxyzine and QT Prolongation: What You Need to Know About the Cardiac Risk

Posted By John Morris    On 19 Nov 2025    Comments (11)

Hydroxyzine and QT Prolongation: What You Need to Know About the Cardiac Risk

Hydroxyzine can cause dangerous heart rhythm problems like QT prolongation and Torsade de Pointes, especially in older adults or those on other medications. Learn who's at risk, what doses are safe, and safer alternatives.

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Tirzepatide for Weight Loss: How Dual Incretin Therapy Works and What to Expect

Posted By John Morris    On 19 Nov 2025    Comments (11)

Tirzepatide for Weight Loss: How Dual Incretin Therapy Works and What to Expect

Tirzepatide (Zepbound) is a dual GLP-1 and GIP agonist that helps with weight loss by targeting appetite, fat storage, and metabolism. Clinical trials show up to 22.5% weight loss, outperforming other drugs like semaglutide. Side effects are common but manageable with slow titration.

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Lopinavir/Ritonavir Boosting: How CYP3A4 Interactions Impact Drug Safety and Efficacy

Posted By John Morris    On 18 Nov 2025    Comments (12)

Lopinavir/Ritonavir Boosting: How CYP3A4 Interactions Impact Drug Safety and Efficacy

Lopinavir/ritonavir boosts HIV treatment by inhibiting CYP3A4, but this causes dangerous interactions with dozens of common drugs. Learn how it works, which medications to avoid, and why it's fading from use in high-income countries.

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