Domperidone: Uses, Safety, and How to Buy It

Domperidone is a medication often used to relieve nausea, vomiting, and symptoms of slow stomach emptying called gastroparesis. It works by blocking dopamine receptors in the gut and speeding up how fast food moves through the stomach. Doctors prescribe it for short-term nausea and for some cases of low milk supply in breastfeeding mothers, though that use is off-label and needs careful medical advice.

Dosage & duration

Before you take domperidone, know the safety issues. It can affect the heart rhythm in some people, especially at higher doses or when combined with other drugs that prolong the QT interval. If you have heart disease, low potassium, or take medicines like certain antifungals, macrolide antibiotics, or some antidepressants, tell your doctor. Many health agencies recommend ECG monitoring in higher-risk patients or avoiding domperidone when interacting drugs are present.

How much and how long depends on why you take it. Typical doses range from 10 mg to 20 mg taken up to three times daily before meals, but exact dosing should come from your doctor. Treatment is usually short term. Long-term use raises the risk of side effects like movement disorders or heart problems, so ask your provider for a clear plan and follow-up checks.

Buying and safety tips

If you are shopping online for domperidone, be cautious. Choose pharmacies that require a valid prescription, show a licensed pharmacist contact, and have clear return and privacy policies. Avoid sites that sell prescription drugs without any prescription or push unusually low prices. Check reviews, verify the pharmacy’s registration in its country, and use secure payment methods. If a deal looks too good, it probably is.

Alternatives to domperidone include metoclopramide, erythromycin (short-term), and ondansetron, depending on the cause of symptoms. Each has its own side effects and risks — metoclopramide can cause movement disorders, and erythromycin may cause interactions and tolerance. Discuss alternatives with your clinician, especially if you have existing heart or neurological issues.

Watch for common side effects like dry mouth, abdominal cramps, and drowsiness. Seek urgent care for symptoms like fainting, chest pain, or a racing heartbeat. For breastfeeding mothers using domperidone to boost milk supply, work closely with lactation specialists and your prescriber to weigh benefits and risks and to choose the lowest effective dose.

Want to learn more? Read our reviews and buying guides that cover safe online pharmacies, drug interactions, and alternatives. We gather practical tips so you can make informed choices about domperidone and other medicines. Ask your healthcare team for personalized advice — this page is a starting point, not a prescription.

Keep a simple checklist when discussing domperidone with your clinician: reason for use, expected duration, dose, possible heart risks, and other medicines you take. Ask whether ECG monitoring is needed and how often. If you start to feel unusual symptoms, stop the drug and contact your doctor right away. Keep a written record of side effects and prescriptions. That record helps your provider adjust treatment or choose safer alternatives quickly. Share that information with pharmacists and family members when needed.